B-complex

B-complex

Supplements Over the counter

Prescription status is set country by country — the label where you live is the one that applies.

Beta: the medication section is still being tested, and its data may contain errors. Do not rely on it for a decision about your own treatment.

What it is

A B-complex supplement combines the water-soluble B vitamins, including thiamine, riboflavin, niacin, B6, folate and B12. They work as coenzymes in the reactions that release energy from carbohydrate, fat and protein, and in the one-carbon pathways that build DNA and red blood cells. Such products are used to correct or prevent deficiency of these vitamins and are taken with an eye to energy metabolism.

Times
With food
Morning

A usual adult range, not a national label — the dose and the timing differ by country and by product.

Used for

  • Deficiency
  • Energy

Approved uses differ by country — some of these may be off-label or unapproved where you live.

What to know while taking it

It is taken with food in the morning; these vitamins support daytime energy metabolism, and taking them with a meal reduces stomach upset. They are water-soluble, so what is not needed is excreted; riboflavin is strongly coloured and turns urine bright yellow, which is expected and harmless rather than a sign of a problem. The values that show whether the B vitamins are doing their job are vitamin B12, folate and homocysteine, since homocysteine rises when B12, folate or B6 are lacking and falls as they are replaced.

When to see a doctor

Numbness, tingling, unsteady walking, a sore tongue or persistent unexplained fatigue can point to a B12 deficiency that a supplement may mask rather than resolve, so see a doctor for testing instead of continuing on guesswork.

Worth knowing

  • Turns urine bright yellow

Markers to watch

Reference information, not medical advice. Discuss any change with your doctor.