Rivaroxaban

Rivaroxaban

Antithrombotics Prescription only ATC code: B01AF01

What it is

Rivaroxaban is an oral anticoagulant that blocks factor Xa, a key enzyme in the clotting cascade, so clots form more slowly and existing ones are less likely to grow. It is used to treat and prevent thrombosis and to lower the risk of stroke in people with atrial fibrillation. Unlike older anticoagulants it works at a fixed dose without routine clotting tests.

Typical dose
10–20 mg
1× a day
Times
With food

Used for

  • Thrombosis
  • Stroke prevention

What to know while taking it

The tablet is taken with food, which helps the body absorb it reliably, and at a steady time each day, because the effect fades within a day and a missed dose leaves a real gap in protection. Combining it with acetylsalicylic acid, ibuprofen or another anticoagulant such as warfarin adds bleeding risk on top of bleeding risk, so these are avoided unless a doctor has weighed the reason. Because the kidneys clear part of the drug, creatinine and eGFR are checked periodically, and hemoglobin is followed as a signal of slow blood loss. Any surgeon, dentist or endoscopist needs to know about it before a procedure.

When to see a doctor

Bleeding that does not stop, black or bloody stools, pink or brown urine, coughing or vomiting blood, or unusual bruising all mean seeing a doctor. Severe headache, sudden weakness or a fall with a head injury should be assessed the same day, and a doctor decides on any interruption of treatment.

Worth knowing

  • Raises bleeding risk
  • A missed dose matters
  • Tell the surgeon before any operation

Markers to watch

Reference information, not medical advice. Discuss any change with your doctor.