Ketorolac
Ketorolac is a potent non-selective non-steroidal anti-inflammatory drug that blocks both COX-1 and COX-2, cutting prostaglandin production throughout the body. Its analgesic strength approaches that of weak opioids, which is why it is reserved for short-term treatment of moderate to severe pain rather than everyday aches. It is prescription-only.
It is taken with food, and courses are deliberately kept short: the risk of stomach ulceration and bleeding climbs steeply with each additional day of use. It is not combined with warfarin or with other NSAIDs such as ibuprofen, acetylsalicylic acid or diclofenac, since all of these compound bleeding risk. Ketorolac also blocks platelet aggregation, so platelets are monitored alongside hemoglobin, while creatinine reflects the reduced kidney blood flow that makes existing kidney disease a particular caution.
Black stools, blood in vomit or stool, or severe stomach pain mean see a doctor immediately. Easy bruising, nosebleeds or bleeding gums, and any drop in urine output or new swelling, also warrant medical review rather than continuing the course.
Reference information, not medical advice. Discuss any change with your doctor.