Indapamide
Indapamide is a thiazide-like diuretic. It acts on the distal tubule of the kidney to reduce sodium and water reabsorption, and it also relaxes vascular smooth muscle, so blood pressure falls by more than the fluid loss alone would explain. It is used for high blood pressure and for fluid retention.
It can be taken with or without food and is normally a morning medicine, since taking it later means being woken to pass urine. Losses run to potassium and magnesium as well as water, so potassium and sodium are checked, along with uric acid, glucose and creatinine, which this class can move. Low potassium makes the heart more sensitive to digoxin, which is why the combination is watched closely. Adequate fluid matters, and the skin becomes more sensitive to sunlight, so strong sun is best avoided.
Muscle cramps, marked weakness, palpitations, confusion or fainting can point to a low potassium or sodium level and are reasons to see a doctor. The same applies to a painful swollen joint suggesting gout, or to signs of dehydration during hot weather or a stomach upset.
Reference information, not medical advice. Discuss any change with your doctor.