Domperidone
Prescription status is set country by country — the label where you live is the one that applies.
Beta: the medication section is still being tested, and its data may contain errors. Do not rely on it for a decision about your own treatment.
Domperidone is a prokinetic and anti-nausea drug that blocks dopamine receptors in the gut wall and in the chemoreceptor trigger zone, the part of the brainstem that sits outside the blood-brain barrier. The result is faster stomach emptying and a suppressed vomiting reflex. Where it is sold in the EU, its licence covers nausea and vomiting only; a European Medicines Agency review dropped the earlier use for sluggish digestion with fullness and bloating.
A usual adult range, not a national label — the dose and the timing differ by country and by product.
Approved uses differ by country — some of these may be off-label or unapproved where you live.
It is taken before meals on an empty stomach, since it works by moving food along and needs to be acting already while the meal is being emptied; food taken first delays its absorption. It can prolong the QT interval, the heart's electrical recovery time, so it is meant for short courses and combines badly with other QT-prolonging drugs and with medicines that slow its breakdown in the liver, such as certain antifungals and antibiotics. Any existing heart rhythm problem or potassium or magnesium disturbance makes it a poorer choice.
Palpitations, fainting, dizziness, an irregular heartbeat, or nausea that persists past a short course are reasons to see a doctor.
Reference information, not medical advice. Discuss any change with your doctor.