Ceftriaxone
Ceftriaxone is an injectable third-generation cephalosporin antibiotic. It blocks the cross-linking of the bacterial cell wall, killing bacteria as they divide, and it penetrates well into tissues including the central nervous system. It is given for bacterial infections, usually the more serious ones that need a hospital or clinic setting.
It is given by injection or infusion by a health professional rather than taken at home, so timing is set by the course, not by meals. It is never mixed with intravenous calcium in the same line or infusion, because the two can form precipitates. It can increase the effect of warfarin, and it disturbs gut flora, so probiotics are separated in time from the antibiotic. Creatinine, ALT and total bilirubin may be checked, since the drug is cleared by both kidneys and bile, and the full course is completed even once the illness appears to have resolved.
Rash, hives, facial swelling or breathing difficulty after a dose suggests an allergic reaction and needs urgent care. Severe or bloody diarrhoea, yellowing of the skin or eyes, right-sided abdominal pain, unusual bleeding, or a sharp drop in urine output means see a doctor.
Reference information, not medical advice. Discuss any change with your doctor.