Cefixime

Cefixime

Antibiotics Prescription only ATC code: J01DD08

What it is

Cefixime is an oral cephalosporin antibiotic. It blocks the enzymes that cross-link the bacterial cell wall, so dividing bacteria burst. It is prescribed for bacterial infections and, like all antibiotics, does nothing against viruses.

Typical dose
200–400 mg
1× a day

Used for

  • Bacterial infection

What to know while taking it

It can be taken with or without food, whichever settles better on the stomach. Loose stools are common, since the drug does not distinguish gut bacteria from the target; probiotics can help but are taken a few hours apart from the antibiotic, otherwise the dose kills them on arrival. The kidneys clear it, so creatinine may be checked, particularly where kidney function is already reduced. The full course is completed as prescribed even after symptoms improve, because ending early leaves the hardiest bacteria behind.

When to see a doctor

A rash, hives, swelling of the face or lips, or difficulty breathing after a dose points to an allergic reaction and needs urgent medical attention. Watery or bloody diarrhoea that is severe or persists after the course, or fever that returns, also means see a doctor.

Worth knowing

  • Finish the full course
  • Take probiotics a few hours apart

Interacts with

Markers to watch

Reference information, not medical advice. Discuss any change with your doctor.