Azithromycin

Azithromycin

Antibiotics Prescription only ATC code: J01FA10

What it is

Azithromycin is a macrolide antibiotic. It binds to the bacterial ribosome and stops the bacteria from making the proteins they need, which halts their growth; it stays in tissue long after the last dose, so courses are short. It is used for bacterial infections, commonly of the airways, skin and some sexually transmitted ones.

Typical dose
250–500 mg
1× a day
Times
On an empty stomach

Used for

  • Bacterial infection

What to know while taking it

The tablets are taken with or without food, the capsules on an empty stomach, and either is kept well apart from antacids, whose aluminium and magnesium bind it and blunt absorption; it also interferes with magnesium itself. Probiotics are spaced a few hours away so the antibiotic does not simply wipe them out, and the full course is finished even once symptoms fade. It can raise the effect of warfarin and, with atorvastatin, the risk of muscle injury, and ALT is watched because the liver handles this drug.

When to see a doctor

Azithromycin can lengthen the QT interval, so fainting, palpitations or a racing irregular heartbeat means seeing a doctor promptly. Unexplained muscle pain or weakness, dark urine, yellowing skin, or severe watery or bloody diarrhoea also warrant medical review.

Worth knowing

  • Can prolong the QT interval
  • Finish the full course
  • Take at least 2 hours apart from antacids
  • Take probiotics a few hours apart

Markers to watch

Nutrients affected

  • magnesium — absorption blocked with (Glucose, HOMA-IR, Magnesium)

Reference information, not medical advice. Discuss any change with your doctor.